Obesity Ups the Risk of Chronic Kidney Diseases by 83%: Are Pune Women at Increased Risk?

Pune, 13th March 2018: In a span of 10 to 15 years, deaths due to kidney failure, an advanced-stage outcome of chronic kidney disease (CKD), has doubled in India, with an estimated 1.3 lakh deaths in the age group of 15 to 69 years recorded in 2015. The prevalence of the disease is growing due to increased prevalence of major risk factors such as diabetes, cardiovascular diseases and hypertension, creating significant stress on the healthcare system in India.

It is wellestablished that obesity leads to diabetes, cardiovascular diseases andhypertension, but new research also indicates that it appears to haveadditional independent risk of CKD. Obese people are at 83% increased risk ofCKD and 24.8% CKD in women and 13.8% CKD in men are associated with thecondition. 

“Theconnection of obesity with diabetes, cardiovascular diseases and hypertension,which are the major risk factors for chronic kidney disease, is well known.However, obesity is now also being associated with increased inflammation,increased hormonal sensitivity to blood pressure and metabolic abnormalitiesthat has a direct impact on kidneys. It is interesting to note that 35% ofurban women in Pune are overweight or obese, which can translate into thousandsof women at risk for CKD in future. This is a grave cause for concern becausealthough obesity can be managed, CKD has no cure. The disease is progressiveand gradually leads to kidney failure” said Dr. Ganesh Mhetras,ConsultantNephrologist, Columbia Asia Hospital, Pune

With theInternational Women’s Day around the corner, this year’s awareness campaign forWorld Kidney Day, with the theme “Kidneys and Women’s Health” could not havebeen more appropriate.  

Globally,the disease is considered as the 8th leading cause of death in women, with anestimated 19.5 crore women being affected by the disease, causing around 6 lakhdeaths each year. Studies also suggest that women have a CKD prevalence of 14%against 12% in men. 

“For manypatients who are at the end-stage kidney disease, a stage at which theirkidneys fail to work, dialysis and kidney transplants are the only remainingoptions. As per estimations, over 2 lakh people in the country require kidneytransplant, with a prevalence of around 151 to 232 transplant cases per millionpopulations. There are far more number of people needing kidneytransplants than there are donors. In the Indian scenario, there are addedfactors which elevate the risks of the disease in women. Women have to facemultiple socio-economic challenges that keep the concerns of their healthsecondary to men or family. They fall behind men in terms of timely diagnosis,accesses to healthcare, and receiving treatment. Other than lacking awarenessabout the disease, the biologic conditions such menstrual cycles and pregnancyare conditions purely unique to women, and all this makes them more vulnerableto CKDs”said Dr. Ganesh Mhetras,Consultant, Nephrologist Columbia AsiaHospital,Pune

Kidneydiseases are all the more dangerous because most of them develop slowly andsilently, without the manifestation of any obvious symptoms. They are known toshow real signs only in advance stages, and therefore, it becomes all the moreimportant to get periodic tests done if a person is suffering from an overlyingcondition. It is time that women in the city get cautious about the disease andundergo periodic health evaluation, apart from following a healthy diet andlifestyle.


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